Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Egr2  early growth response 2   (Synonyms: Egr-2, Krox20, Krox-20, NGF1-B, Zfp-25)
Results	Reference
1	J:67296 Adams RH, Diella F, Hennig S, Helmbacher F, Deutsch U, Klein R, The cytoplasmic domain of the ligand ephrinB2 is required for vascular morphogenesis but not cranial neural crest migration. Cell. 2001 Jan 12;104(1):57-69
1	J:126342 Bok J, Brunet LJ, Howard O, Burton Q, Wu DK, Role of hindbrain in inner ear morphogenesis: Analysis of Noggin knockout mice. Dev Biol. 2007 Nov 1;311(1):69-78
1*	J:14356 Carpenter EM, Goddard JM, Chisaka O, Manley NR, Capecchi MR, Loss of Hox-A1 (Hox-1.6) function results in the reorganization of the murine hindbrain. Development. 1993 Aug;118(4):1063-75
1*	J:147160 Chambers D, Wilson LJ, Alfonsi F, Hunter E, Saxena U, Blanc E, Lumsden A, Rhombomere-specific analysis reveals the repertoire of genetic cues expressed across the developing hindbrain. Neural Dev. 2009;4:6
1	J:231470 Chandler RL, Magnuson T, The SWI/SNF BAF-A complex is essential for neural crest development. Dev Biol. 2016 Mar 1;411(1):15-24
1	J:63192 Cheah SS, Kwan KM, Behringer RR, Requirement of LIM domains for LIM1 function in mouse head development. Genesis. 2000 May;27(1):12-21
1*	J:49657 Dufort D, Schwartz L, Harpal K, Rossant J, The transcription factor HNF3beta is required in visceral endoderm for normal primitive streak morphogenesis. Development. 1998 Aug;125(16):3015-25
1*	J:41551 Dupe V, Ghyselinck NB, Wendling O, Chambon P, Mark M, Key roles of retinoic acid receptors alpha and beta in the patterning of the caudal hindbrain, pharyngeal arches and otocyst in the mouse. Development. 1999 Nov;126(22):5051-9
1*	J:55390 Folberg A, Nagy Kovacs E, Luo J, Giguere V, Featherstone MS, RARbeta mediates the response of Hoxd4 and Hoxb4 to exogenous retinoic acid. Dev Dyn. 1999 Jun;215(2):96-107
1*	J:46972 Gavalas A, Studer M, Lumsden A, Rijli FM, Krumlauf R, Chambon P, Hoxa1 and Hoxb1 synergize in patterning the hindbrain, cranial nerves and second pharyngeal arch. Development. 1998 Mar;125(6):1123-36
1	J:143572 Gorivodsky M, Mukhopadhyay M, Wilsch-Braeuninger M, Phillips M, Teufel A, Kim C, Malik N, Huttner W, Westphal H, Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain. Dev Biol. 2009 Jan 1;325(1):24-32
1*	J:278751 Hatakeyama J, Sakamoto S, Kageyama R, Hes1 and Hes5 regulate the development of the cranial and spinal nerve systems. Dev Neurosci. 2006;28(1-2):92-101
1	J:31139 Irving C, Nieto MA, DasGupta R, Charnay P, Wilkinson DG, Progressive spatial restriction of Sek-1 and Krox-20 gene expression during hindbrain segmentation. Dev Biol. 1996 Jan 10;173(1):26-38
1	J:102844 Ishii M, Han J, Yen HY, Sucov HM, Chai Y, Maxson RE Jr, Combined deficiencies of Msx1 and Msx2 cause impaired patterning and survival of the cranial neural crest. Development. 2005 Nov;132(22):4937-50
1	J:104870 Jin O, Harpal K, Ang SL, Rossant J, Otx2 and HNF3beta genetically interact in anterior patterning. Int J Dev Biol. 2001;45(1):357-65
1	J:123924 Kim TH, Goodman J, Anderson KV, Niswander L, Phactr4 regulates neural tube and optic fissure closure by controlling PP1-, Rb-, and E2F1-regulated cell-cycle progression. Dev Cell. 2007 Jul;13(1):87-102
1	J:59069 Klingensmith J, Ang SL, Bachiller D, Rossant J, Neural induction and patterning in the mouse in the absence of the node and its derivatives. Dev Biol. 1999 Dec 15;216(2):535-49
1	J:236825 Langer D, Martianov I, Alpern D, Rhinn M, Keime C, Dolle P, Mengus G, Davidson I, Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation. Nat Commun. 2016 Mar 30;7:11063
1*	J:54107 Levy JE, Jin O, Fujiwara Y, Kuo F, Andrews NC, Transferrin receptor is necessary for development of erythrocytes and the nervous system. Nat Genet. 1999 Apr;21(4):396-9
1*	J:55208 Mechta-Grigoriou F, Garel S, Charnay P, Nab proteins mediate a negative feedback loop controlling Krox-20 activity in the developing hindbrain. Development. 2000 Jan;127(1):119-28
1	J:208408 Prin F, Serpente P, Itasaki N, Gould AP, Hox proteins drive cell segregation and non-autonomous apical remodelling during hindbrain segmentation. Development. 2014 Apr;141(7):1492-502
1	J:162560 Qu Y, Glasco DM, Zhou L, Sawant A, Ravni A, Fritzsch B, Damrau C, Murdoch JN, Evans S, Pfaff SL, Formstone C, Goffinet AM, Chandrasekhar A, Tissir F, Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice. J Neurosci. 2010 Jul 14;30(28):9392-401
1	J:93020 Remacle S, Abbas L, De Backer O, Pacico N, Gavalas A, Gofflot F, Picard JJ, Rezsohazy R, Loss of function but no gain of function caused by amino acid substitutions in the hexapeptide of Hoxa1 in vivo. Mol Cell Biol. 2004 Oct;24(19):8567-75
1*	J:88939 Rhinn M, Lun K, Werner M, Simeone A, Brand M, Isolation and expression of the homeobox gene Gbx1 during mouse development. Dev Dyn. 2004 Feb;229(2):334-9
1	J:75491 Roberts C, Sutherland HF, Farmer H, Kimber W, Halford S, Carey A, Brickman JM, Wynshaw-Boris A, Scambler PJ, Targeted mutagenesis of the Hira gene results in gastrulation defects and patterning abnormalities of mesoendodermal derivatives prior to early embryonic lethality. Mol Cell Biol. 2002 Apr;22(7):2318-28
1	J:166040 Rocha PP, Scholze M, Bleiss W, Schrewe H, Med12 is essential for early mouse development and for canonical Wnt and Wnt/PCP signaling. Development. 2010 Aug;137(16):2723-31
1	J:297650 Roeseler DA, Strader L, ANderson MJ, Waters ST, Gbx2 is required for the migration and survival of a subpopulation of trigeminal cranial neural crest cells. J Dev Biol. 2020;8(33)
1*	J:24115 Shawlot W, Behringer RR, Requirement for Lim1 in head-organizer function [see comments]. Nature. 1995 Mar 30;374(6521):425-30
1*	J:77801 Soo K, O'Rourke MP, Khoo PL, Steiner KA, Wong N, Behringer RR, Tam PP, Twist function is required for the morphogenesis of the cephalic neural tube and the differentiation of the cranial neural crest cells in the mouse embryo. Dev Biol. 2002 Jul 15;247(2):251-70
1*	J:46973 Studer M, Gavalas A, Marshall H, Ariza-McNaughton L, Rijli FM , Chambon P , Krumlauf R, Genetic interactions between Hoxa1 and Hoxb1 reveal new roles in regulation of early hindbrain patterning. Development. 1998 Mar;125(6):1025-36
1*	J:45681 Suda Y, Matsuo I, Aizawa S, Cooperation between Otx1 and Otx2 genes in developmental patterning of rostral brain. Mech Dev. 1997 Dec;69(1-2):125-41
1*	J:40910 Urbanek P, Fetka I, Meisler MH, Busslinger M, Cooperation of Pax2 and Pax5 in midbrain and cerebellum development. Proc Natl Acad Sci U S A. 1997 May 27;94(11):5703-8
1	J:54222 Xu X, Li C, Takahashi K, Slavkin HC, Shum L, Deng CX, Murine fibroblast growth factor receptor 1alpha isoforms mediate node regression and are essential for posterior mesoderm development. Dev Biol. 1999 Apr 15;208(2):293-306
1	J:264530 Zaffran S, Odelin G, Stefanovic S, Lescroart F, Etchevers HC, Ectopic expression of Hoxb1 induces cardiac and craniofacial malformations. Genesis. 2018 Jun;56(6-7):e23221